Principal Investigator
Associate Professor Dr. Sarath Chandra Janga
School of Informatics and Computing
Indiana University & Purdue University Indianapolis (IUPUI)
Department of Medical & Molecular Genetics
Center for Computational Biology & Bioinformatics
Division of Gastroenterology/Hepatology, Department of Medicine
Indiana University School of Medicine
Dr. Janga obtained his PhD (2008-2010) from the MRC Laboratory of Molecular Biology, Darwin College, University of Cambridge, UK. He received his Bachelors and Masters degrees in Bio-chemical Engineering & Biotechnology from Indian Institute of Technology, Delhi and has previously worked in the Laboratory of Computational Genomics, Center for Genomic Sciences, UNAM, Cuernavaca, Mexico where he was involved in understanding bacterial gene regulatory networks in the group of Dr. Julio Collado-Vides. He started his doctoral work at Cambridge in 2007. He was an Institute for Genomic Biology Fellow, at University of Illinois in Urbana-Champaign, working on applying computational and systems approaches to understanding regulation at post-transcriptional level and using genome mining techniques for identifying novel antibacterial pathways and compounds during his post-doctoral period (2010-2012).
Postdoctoral researchers
Doaa Hassan Salem, PhD
Doaa H. Salem is a machine learning postdoctoral researcher at Janga lab and an adjunct lecturer at Bio-health informatics department at School of Informatics and Computing at IUPUI. Her research interest focuses on the new directions for the application of data mining and machine learning techniques, particularly in computational biology, social networks, and cyber security. Currently her research work emphasizes on the application of machine learning combined with Nanopore technology for detecting modifications in RNA sequences. She is also interested in using machine/deep learning for predicting the association between RNA (particularly lncRNA) and various diseases as well as predicting the genotype-phenotype association.
PhD Students
Swapna Vidhur Daulatabad
Swapna Vidhur Daulatabad completed his Bachelors in Biotechnology and moved to Indianapolis in 2014. He pursued his Master’s degree in Bioinformatics at IUPUI from 2014-2016. He is currently a PhD scholar at SoIC, IUPUI. His research interests are translational bioinformatics, exploring characteristics of non-coding RNA using computational approaches, understanding post transcriptional regulation in the cell using machine learning and systems biology.
Hunter Gill
Quoseena Mir
Quoseena Mir did a post graduation in Biotechnology from BITS Pilani, Hyderabad, India. During her studies, she worked on various projects related to association of SNPs with human diseases and studied extended beta lactamase antibiotic resistance in UTI patients. Quoseena has exposure of research in developmental biology and proteomics at Csir-CCMB, with main focus on understanding regeneration and degeneration in Zebrafish. She is currently a Research Associate in Janga Lab. Her current research interest is to study RNA binding proteins, alternative splicing events in different cell lines and their effect on cell differentiation.
Alexander Krohannon
Xander completed his Bachelor’s in Biochemistry at Rose-Hulman Institute of Technology and recently completed his Master’s in Bioinformatics at IUPUI. He is currently a Ph.D. student in Janga Lab. His current research interests are in using next-generation sequencing (NGS) and other high throughput methods to understand cellular methods of RNA regulation. His previous work includes the development of a CRISPR-Cas13 sgRNA designer.
Master’s Students
Okiemute Omoru
Okiemute completed her bachelor’s degree in Medicine and Surgery from University of Lagos, Nigeria. She is a Master’s student in Janga lab, currently researching on SARS-coV2 interactions with the human genome. Her area of research interest are Precision medicine and cancer genomics.
Neel Sangani
Neel recently finished his bachelor’s in Premed-Biomedical Informatics with Biology conc. at IUPUI. He is currently pursuing his Bioinformatics master’s degree in Janga Lab. He is passionate to improve clinical diagnosis, treatment, and prevention using precision medicine methods. His current research interest focuses on using high-throughput methods to map protein-RNA interactions transcriptome-wide in human cancer cell lines and further build ML/DL models to predict such interplay in understudied cell lines.
Matthew completed his bachelor’s degree in Biochemistry with a minor in bioinformatics from Purdue University. Past research has primarily focused on RNA-RNA interactions and RNA structure in SARS. He is currently a Master’s student in the Janga Lab, with his current research revolving around predicting lncRNA & RBP interactions.
David has completed his bachelor’s degree in Mathematics from Purdue University. He is currently working toward a Master’s degree in Bioinformatics and has worked on RNA-RNA interactions in SARS-CoV-2. Currently he is working on using long-read data to map complete RNA-RNA interactions.
Amulya Saini
Amulya did her post-graduation (2015-2021) in pharmacy from Jawaharlal Nehru Technological University, Hyderabad, India. She has exposure in drug discovery and development, clinical data management and data analysis. She is currently a Graduate Research Assistant in The Janga Lab. Her current research interests include scRNA sequence analysis and using machine learning methods in predicting protein RNA interactions.
Soumith completed his bachelor’s degree in pharmacy from GITAM university, Hyderabad. He is a master’s student working in Janga lab, and his current research interest lies in the CRISPR- CAS RNA targeting system.
Simranjit Kaur Virk
Simranjit Kaur Virk completed her Graduation in Systems biology and Bioinformatics (2014) from Punjab University Chandigarh India. She has worked in U.S. healthcare Industry for 5 years. Now she is a master student of Bioinformatics working in Dr. Janga lab, and her current research interest lies in the using GWAS to find meaningful biological information.
Undergraduate Students
Sahiti Somalraju
Sahiti is an undergraduate studying Biomedical Informatics with a specialization in Bioinformatics at IUPUI. She is intrigued by the role of bioinformatics in precision medicine and its application in diagnosing and treating diseases. Currently, she is investigating DNA-transcription factor interactions using ChIP-Seq data analysis.
Interns/Visiting Scholars
Currently, we’re not hosting any interns/visiting scholars. Go to our Join page for visiting our lab as an intern/visiting scholar.
Alumni
Please click and go to our Alumni page for previous lab members!